CBD isolate is a fine white powder containing 99% pure CBD. This pure crystalline contains only the CBD chemical compound, offering CBD in its most concentrated form. CBD isolate is an all-natural cannabinoid supplement made from hemp oil that's been refined down to a pure state.
Cannabis oils that contain all the compounds except for THC are called "broad spectrum CBD" as they may contain secondary cannabinoids like CBG, CBN, CBC, CBDV.
Cannabidiol, or CBD, is one of at least 85 active cannabinoids identified within the Cannabis plant. It is a major phytocannabinoid, accounting for up to 40% of the Cannabis plant's extract, that binds to a wide variety of physiological targets of the endocannabinoid system within the body. Although the exact medical implications are currently being investigated, CBD has shown promise as a therapeutic and pharmaceutical drug target. In particular, CBD has shown promise as an analgesic, anticonvulsant, muscle relaxant, anxiolytic, antipsychotic and has shown neuroprotective, anti-inflammatory, and antioxidant activity, among other currently investigated uses [6, 5]. CBD's exact place within medical practice is still currently hotly debated, however as the body of evidence grows and legislation changes to reflect its wide-spread use, public and medical opinion have changed significantly with regards to its usefulness in a number of medical conditions ranging from anxiety to epilepsy.
the endocannabinoid system consists of the endogenous cannabinoids (endocannabinoids), cannabinoid receptors and the enzymes that synthesise and degrade endocannabinoids. Many of the effects of cannabinoids and endocannabinoids are mediated by two G protein-coupled receptors (GPCRs), CB(1) and CB(2), although additional receptors may be involved. CB(1) receptors are present in very high levels in several brain regions and in lower amounts in a more widespread fashion. These receptors mediate many of the psychoactive effects of cannabinoids. CB(2) receptors have a more restricted distribution, being found in a number of immune cells and in a few neurones. Both CB(1) and CB(2) couple primarily to inhibitory G proteins and are subject to the same pharmacological influences as other GPCRs. Thus, partial agonism, functional selectivity and inverse agonism all play important roles in determining the cellular response to specific cannabinoid receptor ligands.
To understand the human endocannabinoid system, it’s helpful to know a little about one of the most fundamental concepts in biology: homeostasis.
Homeostasis is the concept that most biological systems are actively regulated to maintain conditions within a narrow range. Our body doesn’t want its temperature to be too hot or too cold, blood sugar levels too high or too low, and so on. Conditions need to be just right for our cells to maintain optimum performance, and exquisite mechanisms have evolved to draw them back to the Goldilocks zone if they move out. The body’s endocannabinoid system (ECS) is a vital molecular system for helping maintain homeostasis—it helps cells stay in their Goldilocks zone.
Hemp can be grown as a renewable source for raw materials that can be incorporated into thousands of products. Its seeds and flowers are used in health foods, organic body care, and other nutraceuticals.
Terpenes are the aromatic components of the cannabis plant’s essential oils and they play an important therapeutic role. Terpenes are very small, volatile molecules created by the cannabis plant as an evolutionary adaptation to simultaneously attract and repel certain insects and animals. .
Homeostasis, from the Greek words for "same" and "steady," refers to any process that living things use to actively maintain fairly stable conditions necessary for survival. The term was coined in 1930 by the physician Walter Cannon. His book, The Wisdom of the Body, describes how the human body maintains steady levels of temperature and other vital conditions such as the water, salt, sugar, protein, fat, calcium and oxygen contents of the blood. Similar processes dynamically maintain steady-state conditions in the Earth's environment.
Homeostasis has found useful applications in the social sciences. It refers to how a person under conflicting stresses and motivations can maintain a stable psychological condition. A society homeostatically maintains its stability despite competing political, economic and cultural factors. A good example is the law of supply and demand, whereby the interaction of supply and demand keeps market prices reasonably stable.
Beyond cannabis, there are other plants and flowers that also appear to interact with the human endocannabinoid system. Some plants on this intriguing list do produce actual cannabinoid chemical compounds. Others produce compounds that mimic cannabinoids.
Cannabinoids are chemical compounds. They are produced in plants, and naturally by the human body. The latter group are known as endocannabinoids or “endogenous cannabinoids.”
Phytocannabinoids are cannabinoids produced by plants. Believe it or not, many plants beyond cannabis produce phytocannabinoids.
Beyond that, however, there are also substances called cannabimimetic compounds that mimic cannabinoid properties when consumed. Specifically, they engage with the endocannabinoid system (ECS).
What are these wonders of nature? You probably have already heard of them, even if you did not know all the details. Interestingly enough, many plants containing phytocannabinoids or cannabimimetic compounds are referred to as “superfoods”.
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